co-author

Trans Fat May Lead to Worse Memory, According to a UC San Diego Study

Dietary trans fatty acids (dTFA) are used in foods to improve taste, texture and durability.

Men who have more dietary trans fat in their meals may have worse memory, according to a newly released study by the UC San Diego School of Medicine.

On Tuesday, the Food and Drug Administration (FDA) said they would begin to phase the acid, which they previously called unsafe, out of foods.

Dietary trans fatty acids (dTFA), which are used in foods to improve taste, texture and durability, were linked by researchers to worse memory in men aged 45 and younger.

The study looked at 1,018 men and women who completed a dietary survey and a memory test. Men that consumed trans fat aged 45 and younger saw their performance drop 0.76 words for every additional gram of trans fat consumed.

“Trans fats were most strongly linked to worse memory in men during their high productivity years,” said Beatrice A. Golomb, MD, PhD, lead author and professor of medicine at UC San Diego School of Medicine said in a statement. “Trans fat consumption has previously shown adverse associations to behavior and mood—other pillars of brain function. However, to our knowledge a relation to memory or cognition had not been shown.”

Men with the highest observed trans fat levels in the study recalled an expected 12 fewer words, compared to men that consumed no trans fats.

The results were consistent when adjusting for age, exercise, ethnicity and mood.

The acids have previously been linked to negative effects on general health and are no longer recognized as safe by the FDA.

“As I tell patients, while trans fats increase the shelf life of foods, they reduce the shelf life of people,” said Golomb.

Alexis K. Bui of UC San Diego was a co-author of the study.

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