Bob Hope Airport's Runway 15-33, the airport's longest runway and the one used for nighttime departures, was without power Thursday evening, airport officials said.
Crews worked on the outage since Wednesday night. Sometime Wednesday night, airport runway light bulbs experienced multiple burnouts, according to Victor Gill, spokesman for the airport.
The system was restored at about 5:30 a.m.
The airport accepted arrivals on a different runway during the outage.
Information on flight cancellations or delays will be posted on bobhopeairport.com, where the following statement was posted: "With the Runway 15-33 lighting system out of order, the commercial air carriers, depending on their respective Standard Operating Procedure, may not allow their aircraft to depart the airport."
Many airlines, including Jet Blue, Alaska, Southwest and United, canceled most of their flights Thursday night, Gill said.
Travelers were advised to contact their airlines before heading to the airport.
City News Service contributed to this report.