A nice bounce back by the Rams with a 26-20 win over New Orleans that followed a loss at Minnesota.
This one can be tricky — witness what the undermanned Cardinals did to Jacksonville last Sunday.
These teams went at it in London in October, a 33-0 Rams win that was Arizona's worst performance and cost it QB Carson Palmer (broken left arm).
"Preparation during the week for us is important," said L.A. Rams receiver Sammy Watkins about the matchup. "When we fall off, we lose. Make no mistake, they're going to come out and play hard. They're going to have that 33 to nothing in the back of their heads and they're going to play with an edge. We're going to have to come out and fight. It's not going to be a blowout game."
Los Angeles has displayed balance on both sides of the ball and was especially hard on Adrian Peterson, who rushed for 21 yards on 11 carries in London.
Peterson is expected to miss the game with an injury on Sunday.
An LA win would even the all-time series, which now is 38-37-2 for the Cardinals. It would also give the Rams a season sweep of the Cardinals.
Fantasy Football Start/Sit:
Start: Jared Goff, Todd Gurley, Cooper Kupp, Larry Fitzgerald, Sammy Watkins, Gerald Everett, Greg Zuerlein, Rams Defense
Sit: Blaine Gabbert, Kerwynn Williams, D.J. Foster, Jaron Brown, John Brown, Tavon Austin, Josh McReynolds, Chad Williams, Ricky Seals-Jones, Tyler Higbee, Phil Dawson, Cardinals Defense.
Betting Odds (Courtesy of Bovada):
Rams: -7 (-110)
Cardinals: +7 (-115)
Prediction: 30-14 Rams
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The Associated Press contributed to this story.