Police were pursuing a vehicle in the San Bernardino area Monday night.
The chase led them down to San Diego County at about 9:15 p.m.
Driving down De Luz Road in Fallbrook, the suspects made a sharp turn into a creek bed and bailed out of the car.
The man and woman inside took off on foot, but deputies quickly closed in with the help of K9 units.
One of the dogs bit a suspect, San Diego County Sheriff's officials say.
Law enforcement took both into custody and detained them on a long list of charges.
The chase began on the 10 Freeway in San Bernardino County before the driver led police to the 15 Freeway headed toward Murrieta before exiting and beginning a pursuit on windy mountain roads.