Veterinarians and volunteers at the Middletown Animal Hospital have been working around the clock to rescue and treat injured animals.
Some of the animals have suffered serious burns from the Valley Fire and have been transported to the University of California, Davis. Other animals being cared for are in need of a safe place with food and water.
Donations and volunteers have been pouring in to the hospital.
Many animal lovers are thanking the vets and volunteers for helping pets survive and hopefully return to their families.
The Valley Fire burning in Lake, Napa and Sonoma counties stood at 73,700 acres and was 40 percent contained, Cal Fire officials said Friday.
The blaze, which started at 1:24 p.m. Saturday in the area of Cobb in Lake County, has killed at least three people and injured four firefighters.
Cal Fire officials said at least 585 homes and hundreds of other structures have been destroyed, and at least 7,800 other residential and commercial structures were still threatened.
The cause of the fire remains under investigation.