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With her co-workers cheering her on, an intensive care unit nurse at Kaiser Permanente Los Angeles Monday received one of the first doses in the state of a long-awaited vaccine to prevent COVID-19. Helen Cordova sat patiently and joked with other medical personnel as she was given the Pfizer vaccine — administered with a shot in her right arm...

Orange County Monday set new records for coronavirus diagnoses and hospitalizations as its intensive care units reached zero capacity in the state’s “adjusted” category and sheriff’s officials wrangled with an escalating outbreak in the jails.

Riverside County health officials Monday reported 6,741 newly diagnosed coronavirus cases and 13 virus-related deaths since Friday, as the number of available licensed intensive care unit beds countywide dwindled to zero.

A California man sentenced to death for the 1995 torture slaying of an Orange County teenager died early Monday of unknown causes, prison officials said.

The USC Trojans will be playing in Friday’s Pac-12 Football Championship Game this Friday, but they won’t be playing the team they expected.

Parking fees will be temporarily waived in some of downtown Santa Monica’s ‘s public parking structures through Christmas Day to attract shoppers to the Third Street Promenade and elsewhere.

An important decision is expected this week on whether the monarch butterfly should receive federal designation as a threatened species.

Los Angeles Unified School District campuses would be an ideal setting for administering COVID-19 vaccines to students and their families, Superintendent Austin Beutner said Monday, while again imploring elected officials to provide financial support for schools to prepare for an eventual return to in-person instruction.

Officials in Anaheim, Fullerton and Brea reported that smoke from the Sanderson Fire south of Beaumont in Riverside County was visible Sunday, but stressed that there was no wildfire in Orange County.

Two deputies involved in the killing of Andres Guardado have been temporarily “relieved of duty in response to an unrelated investigation,” the sheriff’s department announced Friday night.

Initial allocations of COVID-19 vaccine are expected to arrive in Southern California as early as this weekend. Here’s what happens next.

“Play free.” That was the advice given to Los Angeles Lakers guard Talen Horton-Tucker ahead of his second preseason game on Sunday night. In his first preseason game on Friday, Horton-Tucker showed flashes of brilliance. He played so well in that contest that he caught the attention of 2019 NBA Finals MVP Kawhi Leonard, who needed conf...

At least one person died Sunday night when a vehicle slammed into a car-repair shop in Corona, and authorities were searching for the driver who ran away from the scene.