All lanes of the southbound 5 Freeway were shut down temporarily in Burbank on Sunday after a multi-vehicle crash, according to the California Highway Patrol.
The California Highway Patrol and fire crews were on scene treating people injured in the crash.
A SigAlert was issued in the area of the 5 Freeway near the Alameda Avenue exit.
It was not clear how many people were injured.
At around 11:46 p.m., CHP reported all lanes were back open.
No further details were immediately available.